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[1]岳喜成,周 锐,陈 刚,等.术前超声疑似甲状腺乳头状癌患者对侧甲状腺结节恶性风险的临床研究[J].宁夏医科大学学报,2021,(02):145-148.[doi:10.16050/j.cnki.issn1674-6309.2021.02.009]
 YUE Xicheng,ZHOU Rui,CHEN Gang,et al.The Clinical Correlation Study of Malignant Risk of Contralateral Thyroid Nodule in Patients with Suspected Thyroid Papillary Carcinoma by Preoperative Ultrasound[J].Ningxia Medical University,2021,(02):145-148.[doi:10.16050/j.cnki.issn1674-6309.2021.02.009]
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术前超声疑似甲状腺乳头状癌患者对侧甲状腺结节恶性风险的临床研究(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2021年02期
页码:
145-148
栏目:
临床医学
出版日期:
2021-02-28

文章信息/Info

Title:
The Clinical Correlation Study of Malignant Risk of Contralateral Thyroid Nodule in Patients with Suspected Thyroid Papillary Carcinoma by Preoperative Ultrasound
文章编号:
1674-6309(2021)02-0145-04
作者:
岳喜成 周 锐 陈 刚 李煊赫 姚廷敬
(蚌埠医学院第一附属医院肿瘤外科,蚌埠 233003)
Author(s):
YUE Xicheng ZHOU Rui CHEN Gang LI Xuanhe YAO Tingjing
(Department of Oncology, the First Affiliated Hospital of Bengbu Medical College,Bengbu 233003, China)
关键词:
甲状腺乳头状癌 对侧甲状腺结节恶性程度
Keywords:
papillary carcinoma of thyroidcontralateral thyroid nodulegrade malignancy
分类号:
R736.1
DOI:
10.16050/j.cnki.issn1674-6309.2021.02.009
文献标志码:
A
摘要:
目的 探讨超声疑似甲状腺乳头状癌患者对侧甲状腺恶性结节的影响因素。方法 收集266例术前超声疑似甲状腺乳头状癌患者的临床资料,根据其对侧甲状腺结节是否为恶性分为对侧恶性结节组与对侧良性结节组,比较两组患者的临床特征,并分析对侧甲状腺恶性结节的影响因素。结果 266例术前超声疑似乳头状癌患者中129例合并对侧甲状腺乳头状癌,137例患者对侧未发现甲状腺乳头状癌;45岁及以上患者合并对侧恶性结节比例较高(P<0.05)。两组患者在肿瘤大小、肿瘤位置、浸润程度、是否存在病灶钙化或病灶血管化、中央区淋巴结转移情况方面差异均有统计学意义(P均<0.05)。多因素分析结果显示,甲状腺乳头状癌患者合并对侧甲状腺结节恶性的危险因素有肿瘤大小<1 cm(OR=3.561)、肿瘤位置为上极(OR=2.204)、浸润累及包膜(OR=2.161)、病灶钙化及血管化(OR=4.521/7.612)、中央区淋巴结转移(OR=1.932)。结论 肿瘤<1 cm、肿瘤位于上极、浸润累及包膜、病灶钙化及血管化、中央区淋巴结转移的甲状腺乳头状癌患者合并对侧腺体结节恶性率更高。
Abstract:
Objective To investigate the influencing factors of contralateral thyroid malignant nodules in patients with suspected papillary thyroid carcinoma. Methods The clinical data of 266 patients with thyroid papillary carcinoma suspected by preoperative ultrasound were collected and divided into contralateral malignant nodule group and contralateral benign nodule group according to whether the contralateral thyroid nodules were malignant or not. Results Among 266 patients suspected of papillary carcinoma by ultrasonography,129 cases were associated with contralateral papillary thyroid carcinoma,137 cases were not found with contralateral papillary thyroid carcinoma;the proportion of patients aged 45 years and above with contralateral malignant nodules was higher(P<0.05). There were statistically significant differences in tumor size,tumor location,degree of invasion,presence of calcification or vascularization,and lymph node metastasis in the central region between the two groups(P all<0.05). Multivariate analysis showed that the risk factors of papillary thyroid carcinoma patients with contralateral thyroid nodule malignancy were tumor size less than 1 cm(OR=3.561),tumor location at the upper pole(OR=2.204),invasion of capsule(OR=2.161),calcification and vascularization(OR=4.521/7.612)and central lymph node metastasis(OR=1.932). Conclusion The malignant rate of thyroid papillary carcinoma patients with tumor <1 cm,tumor located in the upper pole,infiltrating capsule,lesion calcification and vascularization,central lymph node metastasis was higher.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2020-01-08
作者简介:岳喜成(1972—),男,硕士,副主任医师,研究方向:甲状腺乳腺肿瘤。E-mail:yuexicheng@163.com
更新日期/Last Update: 1900-01-01