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[1]卢晓操,王晓琳.慢性心力衰竭患者微型营养评估与血红蛋白、NT-pro BNP 关系及其预后评估价值分析[J].宁夏医科大学学报,2021,(02):124-128.[doi:10.16050/j.cnki.issn1674-6309.2021.02.004]
 LU Xiaocao,WANG Xiaolin.Relationship between Hemoglobin, NT-pro BNP and the Outcome of Chronic Heart Failure MNA and the Effect of Malnutrition on Its Prognosis[J].Ningxia Medical University,2021,(02):124-128.[doi:10.16050/j.cnki.issn1674-6309.2021.02.004]
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慢性心力衰竭患者微型营养评估与血红蛋白、NT-pro BNP 关系及其预后评估价值分析(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2021年02期
页码:
124-128
栏目:
临床医学
出版日期:
2021-02-28

文章信息/Info

Title:
Relationship between Hemoglobin, NT-pro BNP and the Outcome of Chronic Heart Failure MNA and the Effect of Malnutrition on Its Prognosis
文章编号:
1674-6309(2021)02-0124-05
作者:
卢晓操1 王晓琳2
(1. 辽宁省丹东市中心医院心内科,丹东 118000; 2. 辽宁省丹东市中心医院麻醉科,丹东 118000)
Author(s):
LU Xiaocao1 WANG Xiaolin2
(1. Department of Cardiology, Dandong Central Hospital in Liaoning,Dandong 118000,China; 2. Department of Anesthesiology, Dandong Central Hospital in Liaoning,Dandong 118000,China)
关键词:
慢性心力衰竭MNA结果血红蛋白NT-pro BNP营养不良预后
Keywords:
chronic heart failureMNA resultshemoglobinNT-pro BNPmalnutritionprognosis
分类号:
R541.6+1
DOI:
10.16050/j.cnki.issn1674-6309.2021.02.004
文献标志码:
A
摘要:
目的 探讨慢性心力衰竭(chronic heart failure,CHF)患者微型营养评估(micro nutrition assessment,MNA)与血红蛋白(Hb)、氨基酸N端脑钠肽前体(NT-pro BNP)的关系,并分析MNA在预后评估方面的价值。方法 选取2018年6月至2019年12月收治的63例CHF患者,基于改良MNA结果,分为营养良好组(MNA≥12分,29例)与营养不良组(MNA<12分,34例),比较两组患者性别、年龄、体质量指数(BMI)、基础疾病、心功能、总胆固醇(TC)、三酰甘油(TG)、血清清蛋白(ALB)、前清蛋白(PA)、Hb、肌酐(Cr)、NT-pro BNP。结果 营养良好组患者年龄、NT-pro BNP均低于营养不良组(P均<0.05),MNA评分、ALB、PA、HB均高于营养不良组(P均<0.05)。偏相关分析结果显示,ALB、PA、Hb与MNA评分呈正相关,NT-pro BNP与MNA评分呈负相关(P均<0.05)。营养不良组不良事件发生率要高于营养良好组,随时间推移,CHF患者不良事件发生率逐渐增加。ROC曲线分析发现,ALB、PA、Hb、NT-pro BNP的AUC分别为0.644、0.617、0.612、0.672。结论 ALB、PA、Hb、NT-pro BNP与MNA结果密切相关,评估CHF患者不良事件发生风险的价值一般。
Abstract:
Objective To explore the relationship between the results of micro nutrition assessment(MNA)and hemoglobin,NT-pro BNP in patients with chronic heart failure,and analyze the value of MNA in prognostic evaluation. Methods From June 2018 to December 2019,63 patients with CHF who were admitted to our department of cardiology were divided into good nutrition group(MNA≥12,29 cases)and nutrition adverse group(MNA<12,34 cases). The clinical data of the two groups were compared,including gender,age,BMI,underlying disease,cardiac function,total cholesterol(TC),triglyceride(TG),serum albumin(ALB),prealbumin(PA),hemoglobin(Hb),creatinine(Cr)and amino acid N-terminal brain natriuretic peptide precursor(NT-pro BNP). Results The age and NT-pro BNP of the well-nourished group were significantly lower than those of the malnourished group(P all<0.05),and the MNA score,ALB,PA and HB were significantly higher than those of the malnourished group(P all<0.05). Partial correlation analysis showed that ALB,PA,Hb and MNA scores were significantly positively correlated,and NT-pro BNP was significantly negatively correlated with MNA scores(P all<0.05). The incidence of adverse events in the malnutrition group was significantly higher than that in the well-nourished group,and the incidence of adverse events in CHF patients gradually increased over time.ROC curve analysis found that the AUC of ALB,PA,Hb and NT-pro BNP were 0.644,0.617,0.612 and 0.672. Conclusion ALB,PA,Hb and NT-pro BNP are closely related to the results of MNA,but they are of general value in predicting the occurrence of adverse events.

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备注/Memo

备注/Memo:
收稿日期:2020-06-10
作者简介:卢晓操(1981—),学士,副主任医师,从事心内科研究工作。E-mail:luxiaocao2019@163.com
更新日期/Last Update: 1900-01-01