|本期目录/Table of Contents|

[1]康向飞,崔亚男,李文峰,等.肺炎克雷伯菌血流感染预后危险因素分析[J].宁夏医科大学学报,2019,(12):1258-1261.[doi:10.16050/j.cnki.issn1674-6309.2019.12.016]
 KANG Xiangfei,CUI Yanan,LI Wenfeng,et al.Prognostic Risk Factors of Klebsiella Pneumoniae Causing BloodStream Infection[J].Ningxia Medical University,2019,(12):1258-1261.[doi:10.16050/j.cnki.issn1674-6309.2019.12.016]
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肺炎克雷伯菌血流感染预后危险因素分析(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2019年12期
页码:
1258-1261
栏目:
经验交流
出版日期:
2020-03-27

文章信息/Info

Title:
Prognostic Risk Factors of Klebsiella Pneumoniae Causing Blood Stream Infection
文章编号:
1674-6309(2019)12-1258-05
作者:
康向飞 崔亚男 李文峰 马 晓 杨立山
(宁夏医科大学总医院,银川 750004)
Author(s):
KANG Xiangfei CUI Yanan LI Wenfeng MA Xiao YANG Lishan
(General Hospital of Ningxia Medical University,Yinchuan 750004,China )
关键词:
肺炎克雷伯杆菌血流感染预后危险因素
Keywords:
klebsiella pneumoniae bloodstream infection prognosis risk factors
分类号:
R378.99+6
DOI:
10.16050/j.cnki.issn1674-6309.2019.12.016
文献标志码:
B
摘要:
目的 分析肺炎克雷伯杆菌院内血流感染(klebsiella pneumoniae bloodstream infection,Kp BSI)预后及其相关危险因素。方法 对宁夏医科大学总医院2011年1月1日至2016年12月31日确诊为Kp BSI的157例患者进行回顾性调查,收集的临床资料包括患者一般情况、基础疾病、介入操作、治疗情况及预后情况等,入院后28天内死亡患者为死亡组,存活患者为存活组。采用Logistic回归分析Kp BSI预后危险因素。结果 存活组与死亡组患者在年龄、感染当日APACHEⅡ评分、感染当日SOFA评分、ICU住院天数、抗生素使用时间、胃管、气管插管/气管切开、尿管、深静脉导管、有创呼吸机、输血、使用质子泵抑制剂和肠外营养等比较差异均具有统计学意义(P均<0.05)。而性别、住院总天数、住院开始至感染时间、抗生素开始使用时间、是否手术和是否使用激素等因素在两组间比较差异均无统计学意义(P均>0.05)。Logistic回归分析发现年龄(OR=1.206)、感染当日APACHEⅡ评分(OR=1.235)、感染当日SOFA评分(OR=2.320)和使用质子泵抑制剂(OR=0.058)是Kp BSI预后的相关危险因素(P均<0.05)。结论 年龄、感染当日病情程度和使用质子泵抑制剂是影响Kp BSI预后的主要危险因素。
Abstract:
Objective To analyze the prognostic risk factors for nosocomial Klebsiella pneumoniae bloodstream infection. Methods A retrospective survey was conducted on 157 patients diagnosed with Kp BSI from January 1,2011 to December 31,2016 in General Hospital of Ningxia Medical University. The clinical data collected include the general condition of the patient, the underlying disease, interventional procedures, treatment status and prognosis etc. Logistic regression analysis was used to analyze prognostic risk factors. Results The age of the survival and non-survival groups, the APACHE II score on the day of infection, the SOFA score on the day of infection, the number of hospital stays in ICU,the time of antibiotic use,gastric tube, tracheal intubation / tracheotomy,urethra,deep vein catheter,invasive ventilator, blood transfusion,use Proton pump inhibitors and parenteral nutrition were compared,and the differences between the groups were statistically significant(P all< 0.05). The differences between the two groups were not statistically significant(P all>0.05) in terms of gender,total hospital stay,time from hospitalization to infection, time to start antibiotics, whether surgery and whether or not to use hormones. Logistic regression analysis revealed age (OR=1.206), APACHE II score on the day of infection (OR=1.235), SOFA score on the day of infection(OR=2.320), and whether or not proton pump inhibitors(OR=0.058) were associated with the risk of Kp BSI prognosis(P<0.05). Conclusion Age, degree of disease on the day of infection, and use of proton pump inhibitors are major risk factors for the prognosis of Kp BSI.

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备注/Memo

备注/Memo:
收稿日期:2019-05-23
作者简介:康向飞,男,硕士,主治医师,研究方向:重症感染性疾病临床与基础研究。E-mail: kxf-2001@163.com
更新日期/Last Update: 2019-12-30