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[1]王齐国,龙训辉,居来提·阿布都克热木,等.不同年龄脓毒症患者血清脂联素与炎性因子相关性分析[J].宁夏医科大学学报,2014,(09):1028-1030.
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不同年龄脓毒症患者血清脂联素与炎性因子相关性分析(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2014年09期
页码:
1028-1030
栏目:
经验交流
出版日期:
2014-09-30

文章信息/Info

Title:
-
作者:
王齐国龙训辉居来提·阿布都克热木
新疆医科大学附属中医院重症医学科,乌鲁木齐 830000
Author(s):
-
关键词:
脓毒血症脂联素炎性因子
Keywords:
-
分类号:
R593
DOI:
-
文献标志码:
B
摘要:
目的研究不同年龄脓毒症患者血清脂联素水平与炎性因子的关系。方法诊断明确的脓毒血症患者201例作为研究对象,根据年龄分为青年组、中年组和老年组,检测各组患者血清中脂联素及IL-1、IL-6和TNF-α的水平,分析脂联素与炎性因子的关系。结果治疗前青年组血清脂联素水平高于中年组和老年组(P<0.05)、青年组血清IL-1、IL-6和TNF-α水平均低于中年组和老年组(P<0.05);血清脂联素水平与年龄呈负相关关系(r=-0.621,P<0.05);血清IL-1、IL-6和TNF-α水平与年龄呈明显正相关(rIL-1=0.654,rIL-6=0.328,rTNF-α=0.314,P<0.05);脂联素与三个炎性因子间均成明显负相关关系(rIL-1=-0.428,rIL-6=-0.746,rTNF-α=-0.396,P<0.05)。结论脓毒血症患者炎症反应随年龄增长而加强,其机制可能血清脂联素水平变化有关。
Abstract:
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参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2014-04-01 作者简介:王齐国,男,副主任医师,从事危重医学研究。
更新日期/Last Update: 2014-09-20