|本期目录/Table of Contents|

[1]黑静雅,朱 萌,张 宁.59例胃肠间质瘤临床病理分析[J].宁夏医科大学学报,2013,(11):1264-1267,1310.
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59例胃肠间质瘤临床病理分析(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2013年11期
页码:
1264-1267,1310
栏目:
经验交流
出版日期:
2013-11-20

文章信息/Info

Title:
-
作者:
黑静雅1 朱 萌2 张 宁1
1.宁夏医科大学总医院病理科,银川 750004; 2.西安交通大学医学院,西安 710061
Author(s):
-
关键词:
胃肠间质瘤免疫组织化学CD117CD34S-100DOG-1PDGFR-αDesminKi-67
Keywords:
-
分类号:
R365
DOI:
-
文献标志码:
B
摘要:
目的探讨胃肠间质瘤的病理学和免疫组织化学染色的特点。方法回顾性收集胃肠间质瘤标本59例进行常规病理学染色和免疫组织化学EliVision法检测CD117、CD34、S-100、DOG-1、PDGFR-α、Desmin和Ki-67的表达。结果胃肠间质瘤发病年龄高峰为50~60岁,发病部位集中于胃和小肠,分别占47.46%(28/59)和37.29%(22/59),其余依次为食管6.78%(4/59),结肠、腹腔、腹膜等1.69%(1/59);肿瘤体积大小不等且悬殊,直径0.6~18cm之间;免疫组织化学染色显示CD117、CD34、S-100、DOG-1、PDGFR-α、Desmin和Ki-67阳性表达率分别为81.36%(48/59)、62.71%(37/59)、18.64%(11/59)、91.53%(54/59)、94.92%(56/59)、35.59%(21/59)和27.71%(16/59),各因子与临床病理因素之间的关系显示CD117、CD34和DOG-1与肿瘤部位有关,其它均无关。结论CD117、CD34是胃肠间质瘤诊断的初步检测指标,DOG-1、PDGFR-α可辅助CD117、CD34检测阴性的病例。
Abstract:
-

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2013-02-22 作者简介:黑静雅(1978-),女,宁夏人,主治医师,硕士,从事诊断病理学工作。E-mail:jingya1978@163.com
更新日期/Last Update: 2013-11-20