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[1]王琰娟,米成嵘,王 文.乳腺癌前哨淋巴结的超声造影检查及 与乳腺癌组织ER、PR和HER-2表达的相关性[J].宁夏医科大学学报,2013,(05):528-531.
 WANG Yan-juan,MI Cheng-rong,WANG Wen.The Correlation of Contrast-enhanced Ultrasound in Sentine Lymph Node of Breast Cancer and Expression of ER, PR, HER-2 in Breast Cancer Tissues[J].Ningxia Medical University,2013,(05):528-531.
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乳腺癌前哨淋巴结的超声造影检查及 与乳腺癌组织ER、PR和HER-2表达的相关性(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2013年05期
页码:
528-531
栏目:
论著
出版日期:
2013-05-20

文章信息/Info

Title:
The Correlation of Contrast-enhanced Ultrasound in Sentine Lymph Node of Breast Cancer and Expression of ER, PR, HER-2 in Breast Cancer Tissues
作者:
王琰娟1 米成嵘2 王 文2
1.宁夏医科大学,银川 750004; 2.宁夏医科大学总医院超声科,银川 750004
Author(s):
WANG Yan-juan1 MI Cheng-rong2 WANG Wen2
1.Ningxia Med. Univ.,Yinchuan, 750004; 2.Dept. of Ultrasound, the General Hospital of Ningxia Med. Univ., Yinchuan 750004
关键词:
超声造影 乳腺癌 前哨淋巴结 免疫组织化学 ER PR HER-2
Keywords:
contrast-enhanced ultrasound breast cancer sentine lymph node immunohistochemical ER PR HER-2
分类号:
R737.9
DOI:
-
文献标志码:
A
摘要:
目的 通过分析乳腺癌患者皮下注射超声造影剂(Sono Vue)后腋窝淋巴结的增强情况,检测乳腺癌组织中ER、PR及HER-2的表达,探讨乳腺癌前哨淋巴结超声造影检查的临床价值及其与乳腺癌组织中ER、PR及HER-2表达的相关性。方法 选择女性乳腺癌患者89例,术前经肿块周围皮下注射超声造影剂探查前哨淋巴结并标记,与术后肿块免疫组织化学ER、PR及HER-2的结果做对照分析。结果 本研究89例患者中,乳腺癌组织中ER、PR、HER-2同时为阳性者,超声造影发现其腋窝淋巴结转移率最高(73.3%),HER-2阳性且ER、PR有一者阴性或两者均为阴性者,超声造影发现其腋窝淋巴结转移率次之(57.1%),再次是ER、PR、HER-2均为阴性者(42.9%),超声造影发现其腋窝淋巴结转移率最低者是HER-2阴性且ER、PR有一者阳性或两者均为阳性者(28.0%)。结论 乳腺癌前哨淋巴结的超声造影检查与乳腺癌组织ER、PR及HER-2表达对照研究发现,HER-2是乳腺癌腋窝淋巴结转移的危险因素。
Abstract:
1.Ningxia Med. Univ.,Yinchuan, 750004; 2.Dept. of Ultrasound, the General Hospital of Ningxia Med. Univ., Yinchuan 750004

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备注/Memo

备注/Memo:
收稿日期:2012-11-07 基金项目:宁夏2009年科技攻关项目(宁科计字2009139); 宁夏人事厅2010留学归国人员项目(宁人社发2010516) 作者简介:王琰娟(1979-),女,在读硕士研究生,从事超声诊断学研究。 通信作者:米成嵘,主任医师。chengrongm@hotmail.com
更新日期/Last Update: 2013-05-20