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[1]赵君利,刘 丽,刘 蔚,等.女性指长比与卵巢功能[J].宁夏医科大学学报,2012,(09):864-868.
 ZHAO Jun-li,LIU Li,LIU Wei,et al.The Association between Digit Ratios and Ovarian Function[J].Ningxia Medical University,2012,(09):864-868.
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2012年09期
页码:
864-868
栏目:
论著
出版日期:
2012-09-30

文章信息/Info

Title:
The Association between Digit Ratios and Ovarian Function
作者:
赵君利123 刘 丽1 刘 蔚1 李凤华1 袁莹莹1 李彩艳1
1.宁夏医科大学总医院生殖医学中心,银川 750004; 2.宁夏回族自治区生殖与遗传重点实验室,银川 750004; 3.宁夏医科大学生育力保持省部共建教育部重点实验室,银川 750004
Author(s):
ZHAO Jun-li LIU Li LIU Wei LI Feng-hua YUAN Ying-ying LI Cai-yan
1. Reproductive Center General Hospital of Ningxia Medical University, Yinchuan 750004; 2. Key Laboratory of Genetic and Reproduction, Ningxia Hui Autonomous Region,Yinchuan 750004; 3. Key Lab. of Fertility Preservation and Maintenance, Ministry of Educ
关键词:
指长比 多囊卵巢综合征 卵巢早衰 不孕 卵巢功能
Keywords:
digit ratios polycystic ovarian syndrome premature ovarian failure infertility ovarian function
分类号:
R711.75
DOI:
-
文献标志码:
A
摘要:
目的 探讨指长比与女性不孕、卵巢功能的关系。方法 采用电子游标卡尺测量192例多囊卵巢综合征(PCOS)、26例卵巢早衰(POF)及110例卵巢功能正常女性对照组左(L)、右(R)手各指长,比较组间各指长比。结果 全部女性患者左、右手指长比均呈2D:3D<2D:4D<3D:4D<2D:5D<4D:5D<3D:5D趋势。右手各指长比呈PCOS>对照组>POF组趋势; 左手2D:3D、2D:4D趋势相反POF组>对照组>PCOS组,2D:5DPCOS组>POF>对照组,3D:4D、4D:5D、3D:5D对照组>PCOS组>POF组。三组间除右手2D:3D外各指长比比较差异均有统计学意义,其中PCOS组与对照组左手2D:4D、2D:5D、3D:4D、右手2D:5D、3D:5D、4D:5D差异(t=2.13, 1.98、2.22、-2.97、-2.55、-2.31; P<0.05),PCOS组与POF组2D:3D、2D:4D、2D:5D、3D:4D、3D:5D、4D:5D差异有统计学意义(t=-2.11、2.81、3.20、3.77、3.32、2.10; P<0.05); POF组与对照组左手3D:5D、4D:5D、右手3D:4D差异差异有统计学意义(t=2.54、2.38、2.54; P<0.05)。左、右手比比较PCOS组各指长(t=6.04、9.21、11.04、7.82、10.48、7.38; P<0.01)、对照组除4D:5D 外的各指长比(t=2.07、2.72、2.87、2.08; P<0.05)、POF组4D:5D(t=2.24; P<0.05)右手均显著高于左手。三组间及PCOS与对照组间右手2D:4D分布差异有统计学意义(χ2=16.31、12.14; P<0.05)。结论 指长比高低与本地区女性不孕、卵巢功能可能有关。女性患者指长比有左右手差异。低右手各指长比、高左手2D:3D、2D:4D可能是卵巢功能衰竭的指标,高右手指长比、低2D:3D、2D:4D可能与卵巢功能较强的PCOS不孕有关。
Abstract:
Objective To investigate the association between the digit ratios and infertility, ovarain function among female patients in Ningxia region. Methods Fingers' length was measured twice, using an electronic vernier callipe from photocopies of the ventral surface of the hand, the mean value and were calculated for each finger of the right and left hand. Digit ratios were assessed among 110 females with regular menstrual cycle, normal hormone profiles and without polycystic ovaries(control), 192 females with polycystic ovarian syndrome(PCOS)according to the 2003 Rotterdam criteria and 26 females with premature ovarian failure(POF)in patient population. Results The digit ratios showed the increasing trend from 2D:3D to 2D:4D, 2D:5D, 3D:5D, 4D:5D in both hands. Decreasing trend of each digit ratio in right hand and increasing trend of 2D:3D, 2D:4D in left hand from group PCOS to control to POF, decreasing trend of 2D:5D from group PCOS to POF to control and 3D:5D, 4D:5D from group PCOS to control to POF in left hand were found. Lower 2D:4D, 3D:4D in left hand and higher 2D:5D, 3D:5D, 4D:5D in right hand were presented in PCOS than those in controls(t=2.13, 1.981, 2.22, 2.97, 2.55, 2.31; P<0.05); 3D:5D, 4D:5D in left hand and 3D:4D in left hand showed significant difference between POF and controls(t=2.54, 2.38, 2.54; P<0.05); compared to POF group, PCOS had significant lower 2D:3D in left hand and higher 2D:4D, 2D:5D, 3D:4D, 3D:5D, 4D:5D in right hand(t=-2.11, 2.81, 3.20, 3.77, 3.32, 2.10; P<0.05). Compared to left hand, 2D:3D, 2D:4D, 2D:5D, 3D:5D, 4D:5D in PCOS group(t=6.04, 9.21, 11.04, 7.82, 10.48, 7.38; P<0.01), 2D:3D, 2D:4D, 2D:5D, 3D:5D in control group(t=2.07, 2.72, 2.87, 2.08; P<0.05)and 4D:5D in POF group(t=2.24; P<0.05)in right hand were significant higher. The distribution of right hand 2D:4D was different among groups and between PCOS and controls(χ2=16.31, 12.14; P<0.05)with higher proportion of lower 2D:4D in POF and higher one in PCOS group. Conclusion This finding implies that digit ratios may be associated with ovarian function in female patients. Lower digit ratios in right hand and higher 2D:3D, 2D:4D in left hand and their verse trend may be associate with poorer ovarian function and infertility with higher ovarian function among female patients respectively.

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备注/Memo

备注/Memo:
收稿日期:2012-01-03 基金项目:国家自然基金项目(81060051); 宁夏自然科学基金(NZ11267) 作者简介:赵君利(1968-),女,主任医师,硕士研究生导师,博士,从事生殖医学专业。E-mail:zhaojunlii@yahoo.com.cn
更新日期/Last Update: 2012-09-20