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[1]焦运,关玉华,刘帅伟,等.双重血浆分子吸附治疗慢加急性肝衰竭的临床研究[J].宁夏医科大学学报,2015,(12):1426-1428+1432.[doi:10.16050/j.cnki.issn1674-6309.2015.12.015]
 JIAO Yun,G UAN Yuhua,LIU Shuaiwei,et al.-[J].Ningxia Medical University,2015,(12):1426-1428+1432.[doi:10.16050/j.cnki.issn1674-6309.2015.12.015]
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双重血浆分子吸附治疗慢加急性肝衰竭的临床研究(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2015年12期
页码:
1426-1428+1432
栏目:
论著
出版日期:
2015-12-30

文章信息/Info

Title:
-
作者:
焦运; 关玉华; 刘帅伟; 李玉芳; 胡彦超; 雒夏;
宁夏医科大学总医院感染疾病科;
Author(s):
JIAO Yun;G UAN Yuhua;LIU Shuaiwei;LI Yufang;HU Yanchao;LUO Xia;Department of Infectious Diseasesthe General Hospital of Ningxia Medical University;
关键词:
血浆吸附 慢加急性肝衰竭 肿瘤坏死因子-α 白介素-4
Keywords:
-
分类号:
R575.3
DOI:
10.16050/j.cnki.issn1674-6309.2015.12.015
文献标志码:
-
摘要:
目的探讨双重血浆分子吸附治疗慢加急性肝衰竭的临床效果。方法将54例慢加急性肝衰竭患者,分为治疗组32例及对照组22例,对照组给予内科基础治疗,治疗组在内科基础治疗上加用双重血浆分子吸附治疗,检测患者治疗前及治疗后1周血浆肝功能指标总胆红素(TBIL)、丙氨酸氨基转移酶(ALT)、血浆白蛋白(ALB)、胆碱酯酶(CHE)、凝血酶原活动度(PTA)、血小板(PLT)及肿瘤坏死因子-α(TNF-α)、白介素-4(IL-4)的变化。结果治疗组治疗1周后24例(75%)患者精神食欲不佳、恶心、腹胀等临床症状明显好转,对照组为10例(45%),治疗组高于对照组(P<0.05)。治疗组血浆吸附后1周ALB、CHE、PTA指标较对照组治疗后上升(P<0.05);ALT、TBIL、TNF-α、IL-4较对照组治疗后下降(P<0.01);PLT治疗前后差异无统计学意义(P>0.05)。结论双重血浆分子吸附通过清除炎症因子可以改善患者症状,对慢加急性肝衰竭的有一定治疗效果。
Abstract:
-

参考文献/References:

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备注/Memo

备注/Memo:
【基金】 宁夏自然科学基金(NZ13140)
更新日期/Last Update: 1900-01-01