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[1]夏岑峰,崔丽萍,王绍金,等.血浆蛋白C、蛋白S、抗凝血酶Ⅲ活性变化与急性肺血栓栓塞症相关性研究[J].宁夏医科大学学报,2015,(03):248-251.[doi:10.16050/j.cnki.issn1674-6309.2015.03.005 ]
 XIA Cenfeng,CUI Liping,WANG Shaojin,et al.-[J].Ningxia Medical University,2015,(03):248-251.[doi:10.16050/j.cnki.issn1674-6309.2015.03.005 ]
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血浆蛋白C、蛋白S、抗凝血酶Ⅲ活性变化与急性肺血栓栓塞症相关性研究(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2015年03期
页码:
248-251
栏目:
论著
出版日期:
2015-03-30

文章信息/Info

Title:
-
作者:
夏岑峰; 崔丽萍; 王绍金; 张鹏; 张锦;
宁夏医科大学总医院呼吸与危重症医学科;
Author(s):
XIA Cenfeng;CUI Liping;WANG Shaojin;ZHANG Peng;ZHANG Jin;Department of Respiratory and Critical Care Medicinethe General Hospital of Ningxia Medical University;
关键词:
肺血栓栓塞症 蛋白C 蛋白S 抗凝血酶Ⅲ
Keywords:
-
分类号:
R563.5
DOI:
10.16050/j.cnki.issn1674-6309.2015.03.005
文献标志码:
-
摘要:
目的探讨血浆蛋白C(PC)、蛋白S(PS)、抗凝血酶Ⅲ(AT-Ⅲ)活性变化与肺血栓栓塞症(PTE)发生的关系。方法收集符合纳入标准的PTE患者60例(PTE组),同期存在PTE形成的危险因素的非PTE患者55例(高危组),健康人群60例(对照组),检测患者血浆PC、PS、AT-Ⅲ活性,用比较三组患者Caprini评分和抗凝因子PC、PS、AT-Ⅲ活性的差异。结果 Caprini评分三组间比较差异有统计学意义(P<0.05),PTE组与高危组比较差异无统计学意义(P>0.0167),PTE组和高危组的致PTE危险度高于对照组(P均<0.0167);PTE组、高危组抗凝因子PC、PS、AT-Ⅲ活性均较对照组下降(P均<0.0167);而PTE组与高危组两组间三种因子活性下降比较差异无统计学意义(P>0.0167)。结论临床检测血浆PC、PS、AT-Ⅲ活性降低其易栓风险较健康人群增高,但与PTE的发生可能无关。
Abstract:
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参考文献/References:

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备注/Memo

备注/Memo:
【基金】 2011年宁夏医科大学博士点开放课题
更新日期/Last Update: 1900-01-01