|本期目录/Table of Contents|

[1]沈学然.2型糖尿病血管并发症患者血清同型半胱氨酸和内皮素-1相关性分析[J].宁夏医科大学学报,2015,(01):106-107.[doi:10.16050/j.cnki.issn1674-6309.2015.01.037]
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2型糖尿病血管并发症患者血清同型半胱氨酸和内皮素-1相关性分析(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2015年01期
页码:
106-107
栏目:
经验交流
出版日期:
2015-01-30

文章信息/Info

Title:
-
作者:
沈学然;
河北省张家口市第二医院内一科;
Author(s):
-
关键词:
T2DM Hcy、ET-1 糖尿病血管病变
Keywords:
-
分类号:
R587.2
DOI:
10.16050/j.cnki.issn1674-6309.2015.01.037
文献标志码:
-
摘要:
目的探讨血清同型半胱氨酸(Hcy)、内皮素-1(ET-1)水平与2型糖尿病(T2DM)血发症的相关性。方法选取2012年1月-2013年1月间我院确认为T2DM患者30例,采用双抗体夹心酶联免疫吸附法(ELISA)和循环酶法(enzymatic cycling assay)检测血清Hcy、内皮素-1(ET-1)浓度,并设同期来院体检正常者30例为对照组;分析血清Hcy浓度与T2DM、ET-1水平之间的关系。结果 T2DM患者血清Hcy、ET-1水平显著高于对照组(P<0.05);T2DM合并血管病变患者血清Hcy、ET-1浓度显著高于未合并血管病变患者和对照组(P<0.05),观察组患者血清Hcy和ET-1水平呈明显正相关(r=0.614,P=0.000)。结论表明Hcy可能是通过损伤血管内皮功能而致血管并发症发生。
Abstract:
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参考文献/References:

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备注/Memo

备注/Memo:
【基金】 张家口市科学分析技术研究与发展指导计划项目(1221022D)
更新日期/Last Update: 1900-01-01