|本期目录/Table of Contents|

[1]李正直,丁文清,郑漪,等.宁夏儿童三种血液疾病环境危险因素病例-对照研究[J].宁夏医科大学学报,2007,(03):280-282.
 LI Zheng -zhi,DING Wen -qing,ZHENG Yi,et al.A Case-Control Study on Environmental Risk Factors of Three ChildhoodDiseases on Hemopathy[J].Ningxia Medical University,2007,(03):280-282.
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宁夏儿童三种血液疾病环境危险因素病例-对照研究(PDF)
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《宁夏医科大学学报》[ISSN:1005-8486/CN:64-1029/R]

卷:
期数:
2007年03期
页码:
280-282
栏目:
论著
出版日期:
2007-05-20

文章信息/Info

Title:
A Case-Control Study on Environmental Risk Factors of Three ChildhoodDiseases on Hemopathy
作者:
李正直1丁文清1郑漪2左锋2
1.宁夏医学院公共卫生学院,银川 750004; 2.宁夏医学院附属医院儿科,银川 750 004
Author(s):
LI Zheng -zhi DING Wen -qingZHENG Yiet al
The School of Public Health, Ningxia Med. Coll., Yinchuan 750004
关键词:
白血病 淋巴瘤 再生障碍性贫血 环境危险因素 病例-对 照研究 儿童 宁夏
Keywords:
leukemia lymphoma aplastic anemia environmental risk factors case-control study childhood Ningxia
分类号:
R12
DOI:
-
文献标志码:
A
摘要:
目的 探讨儿童 白血病、淋巴瘤(ML)、再生障碍性贫血(AA)三种血液 疾病的环境危险因素。方法 采用1:2配对的病例-对照 流行病学研 究设计,选择由宁夏医学 院附属医院儿科确诊的儿童白血病、淋巴瘤、再生障碍性贫血患者51例; 同时选择该 院与病例同期住院非血液病患儿99例,通过问卷调查的方法收集两组人群的一般社会 人口学特征 、既往病史、儿童母亲孕期有害物质接触史、室内外环境状况及家族史等信息。 对资料进行单因素与多因素 条件Logistic回归分析。结果 家中养宠物可 增加患三种血液 疾病的危险性 (P<0.10,OR=2.21); 有既往感染史的儿童患三种疾病 比例高于对 照组 (P<0.10,OR=2.44); 居室地面装修材料为放射性材料患三种疾病的危险 性高于对照 组 (P<0.05,OR=3.99); 居室装修后在60d以内入住患白血病的危险性增加( P<0.05,OR =16.2)。结论 家中养宠物、有既往感染史、居室装修是儿童白血病、 ML、AA三种 血液疾病发生的共同危险因素。
Abstract:
Objective To explore the environmental risk factors on leukemi a, aplas tic anemia(AA)and lymphoma of childhood. Methods Using 1:2 mat ched case-contr ol study design, 51 patients with leukemia, AA and lymphoma and 102 controls wit hout above diseases selected from the Affiliated Hosptial of Ningxia Medical col lege were investigated. Information was obtained by questionnaires, which includ ed the general social demographic characteristics, disease history, the history of exposure to the harmful materials during the child's mother pregnancy, indoor and outdoor environmental situation and history of the families. Results The p ets in family was more likely to cause the three diseases(P<0.10,OR= 2.21).Th e results also showed that the proportion of the history on infection in cases w as higher than that in controls (P<0.10,OR=2.44).The statistical si gnificant correlation between the fitment materials emitting radioactivity compounds of t he living room floor and the childhood disease of hemopathy and hemopoietic was found. Moving in the fitment house in less than 60 days after fitment was the ri sk factor of the three diseases(P<0.05,OR=16.2). Conclusion T he findings sug gested that the pets in family, the history on infection and the home house fitm ent might be the common risk factors of the three diseases.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2006-12-30 基金项目:宁夏回族自治区科技攻关项目资助(05GG-20716) 作者简介: 李正直(1957-),男,宁夏人,教授,学士,从事室内环境与人体健康的研究。
更新日期/Last Update: 2007-05-20